Ketamine Infusion Therapy

Information about the
Procedure

Ketamine infusion therapy offers a breakthrough option for individuals struggling with chronic pain or treatment-resistant conditions. Originally used as an anesthetic, ketamine has been shown to affect how pain is processed in the nervous system, making it effective for certain complex pain syndromes. When administered in a controlled clinical setting, it can provide relief where traditional therapies have failed—often with fewer long-term side effects than ongoing medication use.

This treatment is especially valuable for those facing long-term pain that affects daily function and quality of life. Infusion sessions are tailored to each patient and carefully monitored to ensure safety and effectiveness.

Key points about Ketamine Infusion Therapy:

What is it?
Ketamine infusion therapy is used to treat chronic pain conditions and certain mental health conditions that haven’t responded to other treatments.

How is it performed?
Ketamine is administered through an IV over a specified period, typically 40 minutes to 4 hours, depending on the treatment protocol. Vital signs are continuously monitored.

Treatment Benefits
Ketamine infusions can rapidly reduce pain intensity, break cycles of chronic pain, and improve tolerance to other therapies. For some individuals, it can also reduce reliance on opioids or other medications. Because ketamine works differently from most conventional pain treatments, it may offer relief for conditions that haven’t responded to standard approaches.

Who Can Benefit From This Treatment
Ketamine infusion therapy may be appropriate for individuals with conditions such as complex regional pain syndrome (CRPS), neuropathic pain, fibromyalgia, or other chronic pain disorders unresponsive to conventional treatments. Patients who haven’t found relief with medications, physical therapy, or injections may benefit from this alternative approach. A full evaluation is required to determine if ketamine is a safe and appropriate option based on your medical history and treatment goals.

Learn more about Ketamine Infusion Therapy by contacting the Minimally Invasive Spine and Pain Institute—our team is here to help you explore your options.

What to know about
After-Care

Aftercare for Ketamine Infusion Therapy

Following a ketamine infusion, it’s normal to feel drowsy, lightheaded, or slightly disoriented for a few hours. Most patients are monitored for a short time before being discharged and should arrange for someone to drive them home. While side effects are typically mild and temporary, it’s important to rest and avoid activities that require full alertness until the medication has fully worn off. Your provider will give you specific guidance based on your response to treatment.

Tips for a Smooth Recovery

Follow these guidelines to support healing after Ketamine Infusion Therapy:

  • Rest for the remainder of the day and avoid operating vehicles or heavy machinery

  • Stay well-hydrated and eat light meals as your system stabilizes

  • Avoid alcohol, sedatives, or other central nervous system depressants

  • Resume normal activities gradually as you feel more alert and comfortable

  • Report any lingering dizziness, confusion, or unusual symptoms to your provider